Rare cannabinoid Science Popularization: what is CBN
What is CBN and what is its role
If you know about the industrial cannabis market, you are familiar with cannabinoid CBD and THC.
These are not the only cannabinoids produced by cannabis plants. Cannabinoid is a general term, and there are still many cannabinoids to be explored. The previous article popularized CBG for everyone. I believe you have a preliminary understanding of rare cannabinoids. Today, we will popularize cannabinol (CBN) and its role.
In this cannabis plant umbrella, each medicinal compound is unique and different from each other, especially in terms of its effects and benefits. For example, what is the difference between THC and CBD? What is the difference between CBD and CBN?
In today's article, we will delve into the world of CBN and how it affects people's spirit and body.
What is CBN
CBN is the medical abbreviation of cannabinol, cannabinol - a non intoxicating compound. With the aging of plants, the content of CBN will be higher. Therefore, cannabinol is usually present in very high amounts in older cannabis plants. Many people deliberately look for older marijuana for high levels of CBN.
Biologically, cannabinol comes from the decomposition and oxidation of tetrahydrocannabinol from the cannabis plant. Therefore, when thc is exposed to CO 2 and heated, it will be converted to CBN.
In terms of pharmacokinetics, CBN is 1/6 to 1/10 of the potency of THC and CB1 receptor. This compound has a mild mental reaction, but is much lower than tetrahydrocannabinol.
CBN is a by-product of THC, which is usually very low in cannabis strains. Cannabinoid was the first cannabinoid isolated; It was initially thought to be the cause of cannabis causing psychoactive ingredients in humans (before the discovery of THC). Next, we will do a comprehensive science popularization for you. If you have read CBG science popularization, you can skip it.
Endogenous cannabinoid system (ECS)
Endogenous cannabinoids. The nomenclature of cannabinoids discovered later is based on this. The endogenous cannabinoid system (ECS) is one of the most important physiological systems involved in maintaining and establishing human health.
The goal of the system is to maintain internal balance and ensure that our personal maintenance system can maintain a stable internal environment in case of fluctuations or changes in the external environment.
The endocannabinoid system can be described as a signal system in the human body, which is composed of endocannabinoids, endogenous receptors and enzymes, and works simultaneously with most other physiological systems.
These cannabinoids are found in the brain, connective tissue, glands, immune cells and organs throughout the body. Think of ECS as a circular process in our body: bind cannabinoids to our receptors, do what it needs to do, and then use enzymes to decompose them.
After learning about ECs, let's explain how CBD, CBN and thc work in ECs?
CBN and its functions
Chemically, the composition of CBN is very similar to THC. It is thought to bind mainly to CB2 receptors, but may still interact with CB1 receptors. It acts as an agonist of TRPV2 receptor, a naturally occurring protein that helps regulate multiple biological systems in the human body. Because of this, CBN may be effective in helping to reduce inflammation, pain, bone health, lower blood pressure, and treat skin conditions and irritation.
CBD oil and its functions
CBD is a medical term for cannabinoids - it is a non psychoactive cannabinoid derived from the cannabis plant. As a natural compound used in oils, ointments and tinctures, it is designed to provide a feeling of relaxation and calm. Unlike THC, this compound is not "exciting".
Cannabinoid does not directly bind to CB1 and CB2 receptors in the endogenous cannabinoid system (ECS).
However, this cannabinoid interacts indirectly with endogenous cannabinoid receptors and affects them in other ways. Cannabinoid affects these receptors by up regulating other compounds that interact with the receptors of the endogenous cannabinoid system.
CBD and CBN: what is the difference?
CBD and CBN are different. When taken alone, cannabis diphenol (CBD) can make people feel awake and improve their nerve concentration. On the other hand, cannabinol (CBN) may have a similar sedative effect.
When it comes to human appetite, the effects of the two drugs and endogenous cannabinoids are also slightly different. Cannabinoid can be used as a mild appetite inhibitor, and cannabinoid can stimulate people's appetite.
In conclusion, these cannabis compounds are rumored to help alleviate inflammation and pain symptoms.
Regardless of the use of either or both of these compounds, consult your doctor before taking any natural remedies or supplements.
What are the benefits of CBN?
Currently under study, cannabinol shows potential benefits. Please note that the current research on this compound is limited and rare, and few studies have proved its effect on human body.
1. it can stimulate appetite
A 2012 psychopharmacology study analyzed the effects of CBN and CBD rodents and their feeding patterns. Researchers found that cannabinol increased food intake in mice, suggesting that it may be an effective appetite stimulant.
2. it can be used as antibacterial agent
A structural activity study was conducted in 2008 to answer questions about cannabinoids containing antibacterial properties. The researchers tested CBN on antibiotic resistant bacterial strains. They found that cannabinoid acts as an effective antibacterial agent against these resistant strains.
3. may have anti-inflammatory properties
These cannabinoids may be an effective anti-inflammatory agent, which can help those suffering from inflammatory diseases, diseases, diseases, etc. A recent rodent study in 2016 concluded that CBN has been shown to reduce arthritis.
4. it may be a neuroprotective agent
New evidence has begun to focus on cannabis and its effects on nervous system diseases. Evidence from clinical studies in mouse models suggests that cannabinoids may provide some therapeutic benefits for nervous system diseases. Researchers specifically studied amyotrophic lateral sclerosis (ALS) and suggested that CBN could delay the onset of this condition.
Rumors about CBN
If you have heard or read CBN before, you may have seen it discussed and praised as a sedative or super sedative.
Few studies have analyzed the sedative effects of CBN. However, a human study did answer this question in the 1970s. This human study was very small. There were five volunteers. No volunteers reported that the endogenous cannabinoid made them feel sleepy.
Cannabinol is rich in sedative terpenes. These terpenes may be responsible for these sedative effects.
Although cannabis diphenol and tetrahydrocannabinol are the headlines and highlights of the cannabis industry, cannabis phenol is slowly and firmly going bright. Animal and human clinical trials and studies are ongoing to analyze the impact and potential benefits of CBN, but much remains to be done.
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